pFUSE-mIgG2Ae1-Fc1
-
Cat.code:
pfc1-mg2ae1
- Documents
ABOUT
pFUSE-mIgG2Ae1-Fc1 is a cloning plasmid for the generation of a Fc-fusion protein expressing the Fc region (CH2 and CH3 domains) of the murine IgG2 heavy chain mutated L235E + E318A/K320A/K322A and the hinge region. The hinge serves as a flexible spacer between the two parts of the Fc-fusion protein, allowing each part of the molecule to function independently.
pFUSE-mIgG2Ae1-Fc2 additionally features the IL2 signal sequence for the generation of Fc-Fusion proteins derived from proteins that are not naturally secreted.
Reference
Steurer W. et al., 1995. Ex vivo coating of islet cell allografts with murine CTLA4/Fc promotes graft tolerance. J Immunol. 155(3):1165-74.
All products are for internal research use only, and not for human or veterinary use.
SPECIFICATIONS
Specifications
Fc-fusion protein generation
in vitro transfection
Plasmid construct has been confirmed by restriction analysis and sequencing.
CONTENTS
Contents
-
Product:pFUSE-mIgG2Ae1-Fc1
-
Cat code:pfc1-mg2ae1
-
Quantity:20 µg
1 ml of Zeocin® (100 mg/ml)
Shipping & Storage
- Shipping method: Room temperature
- -20°C
- Avoid repeated freeze-thaw cycles
Storage:
Caution:
DOCUMENTS
Documents
Technical Data Sheet
Safety Data Sheet
Plasmid Sequence
Certificate of analysis
Need a CoA ?
