pFUSE-mIgG1-Fc
| Product | Unit size | Cat. code | Docs. | Qty. | Price | |
|---|---|---|---|---|---|---|
|
pFUSE-mIgG1-Fc1 Fc-fusion protein expression plasmid - Murine IgG1 |
Show product |
20 µg |
pfuse-mg1fc1
|
|
||
|
pFUSE-mIgG1-Fc2 Fc-fusion protein expression plasmid - Murine IgG1 |
Show product |
20 µg |
pfuse-mg1fc2
|
|
Fc-fusion protein expression plasmid - Murine IgG1
pFUSE-mIgG1-Fc1 is a cloning plasmid for the generation of a Fc-fusion protein expressing the Fc region (CH2 and CH3 domains) of the murine IgG1 heavy chain and the hinge region.
The hinge serves as a flexible spacer between the two parts of the Fc-fusion protein, allowing each part of the molecule to function independently.
Murine IgG1 displays low ADCC and CDC.
pFUSE-mIgG1-Fc2 additionally features the IL2 signal sequence for the generation of Fc-Fusion proteins derived from proteins that are not naturally secreted.
Back to the topSpecifications
Isotype : IgG1 mouse
Effector Activities : ADCC-, CDC +/-
Protein A binding: +/-
Protein G binding: -
Both plasmids are selectable with Zeocin™.
Back to the toppFUSE Contents
- 20 µg of lyophilized DNA
- 1 ml of Zeocin® (100 mg/ml)
Product is shipped at room temperature