pFUSE-mIgG1-Fc

Fc-fusion protein expression plasmid - Murine IgG1

ABOUT

Fc-fusion protein expression plasmid - Murine IgG1

pFUSE-mIgG1-Fc1 is a cloning plasmid for the generation of a Fc-fusion protein expressing the Fc region (CH2 and CH3 domains) of the murine IgG1 heavy chain and the hinge region.

The hinge serves as a flexible spacer between the two parts of the Fc-fusion protein, allowing each part of the molecule to function independently.

Murine IgG1 displays low ADCC and CDC.

pFUSE-mIgG1-Fc2 additionally features the IL2 signal sequence for the generation of Fc-Fusion proteins derived from proteins that are not naturally secreted.

All products are for internal research use only, and not for human or veterinary use.

SPECIFICATIONS

Specifications

Species
Mouse
Plasmid backbone
pFUSE
Reconstitution buffer
Sterile Water
Quality control

Plasmid construct has been confirmed by restriction analysis and sequencing. Plasmid DNA was purified by ion exchange chromatography and lyophilized.

CONTENTS

Contents

  • Product: 
    pFUSE-mIgG1-Fc1
  • Cat code: 
    pfuse-mg1fc1
  • Quantity: 
    20 µg
Includes:

20 µg of pFUSE-mIgG1-Fc1 plasmid provided as lyophilized DNA 1 ml of Zeocin™ (100 mg/ml)

Shipping & Storage

  • Shipping method:  Room temperature
  • Storage:

    • -20°C

    Caution:

    • Avoid repeated freeze-thaw cycles

DOCUMENTS

Documents

pFUSE-mIgG1-Fc1

Technical Data Sheet

Safety Data Sheet

Plasmid Sequence

Certificate of analysis

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CUSTOMER SERVICE & TECHNICAL SUPPORT

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