pFUSE-mIgG1e2-Fc1
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Cat.code:
pfc1-mg1e2
- Documents
ABOUT
pFUSE-mIgG1e2-Fc1 is a cloning plasmid for the generation of Fc-fusion protein expressing the Fc region (CH2 and CH3 domains) of the murine IgG1 heavy chain with the T252M mutation and the hinge region. The hinge serves as a flexible spacer between the two parts of the Fc-fusion protein, allowing each part of the molecule to function independently.
pFUSE-mIgG1e2-Fc2 additionally features the IL2 signal sequence for the generation of Fc-Fusion proteins derived from proteins that are not naturally secreted.
Nagaoka M. & Akaike T., 2003 Single amino acid substitution in the mouse IgG1 Fc region induces drastic enhancement of the affinity to protein A. Protein Eng. 16(4):243:245.
All products are for internal research use only, and not for human or veterinary use.
SPECIFICATIONS
Specifications
Fc-fusion protein generation
in vitro transfection
Plasmid construct has been confirmed by restriction analysis and sequencing.
CONTENTS
Contents
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Product:pFUSE-mIgG1e2-Fc1
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Cat code:pfc1-mg1e2
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Quantity:20 µg
1 ml of Zeocin® (100 mg/ml)
Shipping & Storage
- Shipping method: Room temperature
- -20°C
- Avoid repeated freeze-thaw cycles
Storage:
Caution:
DOCUMENTS
Documents
Technical Data Sheet
Safety Data Sheet
Certificate of analysis
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