pDRIVE-hCD14
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Cat.code:
pdrive-hcd14
- Documents
ABOUT
CD14 promoter (Monocytic cells) in pDRIVE expression plasmid
CD14 is a receptor for bacterial lipopolysaccharide expressed on the surface of myeloid-derived cells, and is strongly upregulated during monocytic cell differentiation.
Monocyte-specific expression of CD14 is regulated at the transcriptional level.
The CD14 promoter contains a C/EBP [1] and Sp1 [2] site that are critical for tissue-specific regulation of CD14 gene expression.
References:
1. Pan Z. et al. 1999. CCAAT/enhancer-binding protein activates the CD14 promoter and mediates transforming growth factor beta signaling in monocyte development. J Biol Chem 274(33):23242-8.
2. Park S. et al. 2002. Synergistic interaction of MEF2D and Sp1 in activation of the CD14 promoter. Mol Immunol 39(1-2):25.
All products are for internal research use only, and not for human or veterinary use.
SPECIFICATIONS
Specifications
in vitro or in vivo transfection
Monocytic cells
in vitro transfection
Plasmid construct has been confirmed by restriction analysis and full-length ORF sequencing.
CONTENTS
Contents
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Product:pDRIVE-hCD14
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Cat code:pdrive-hcd14
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Quantity:20 µg
1 ml of Zeocin® (100 mg/ml)
Shipping & Storage
- Shipping method: Room temperature
- -20°C
- Avoid repeated freeze-thaw cycles
Storage:
Caution:
DOCUMENTS
Documents
Technical Data Sheet
Plasmid Map and Sequence
Safety Data Sheet
Certificate of analysis
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