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pDRIVE-B29

Product Unit size Cat. code Docs. Qty. Price

pDRIVE-hB29

pDRIVE bearing human B29 promoter - LacZ

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20 µg

pdrive-hb29
+-
$554

pDRIVE5SEAP-hB29

pDRIVE bearing human B29 promoter - SEAP

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20 µg

pdrive5s-hb29
+-
$554

pDRIVE5Lucia-hB29

pDRIVE bearing human B29 promoter - Lucia

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20 µg

pdrive5lc-hb29
+-
$554

pDRIVE-mB29

pDRIVE bearing mouse B29 promoter - LacZ

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20 µg

pdrive-mb29
+-
$554

pDRIVE5SEAP-mB29

pDRIVE bearing mouse B29 promoter - SEAP

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20 µg

pdrive5s-mb29
+-
$554

pDRIVE5Lucia-mB29

pDRIVE bearing mouse B29 promoter - Lucia

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20 µg

pdrive5lc-mb29
+-
$554

B29 promoter (B cells) in pDRIVE expression plasmid

B29 (Igbeta) is a B-cell-specific member of the immunoglobulin gene superfamily that is expressed throughout B-cell development.

The product of the B29 gene is an essential component of the B cell receptor and plays a critical role in B cell development.

The B29 gene lacks either a TATA or a CAAT box and transcription is initiated at multiple sites [1].

The minimal promoter of the human B29 gene is contained within a <200-bp region 5' of these multiple start sites [2].

This minimal promoter exhibits B-cell-specific activity and contains SP1, ETS, OCT, and IKAROS/LYF-1 transcription factor motifs [3].

 

References:

1. Hermanson GG. et al. 1989. Immunoglobulin enhancer and promoter motifs 5' of the B29 B-cell-specific gene. Proc Natl Acad Sci U S A 86(19):7341-5.
2. Omori SA. & Wall R. 1993. Multiple motifs regulate the B-cell-specific promoter of the B29 gene. Proc Natl Acad Sci USA 90(24):11723-7.
3. Thompson AA. et al., 1996. The promoter and 5' flanking sequences controlling human B29 gene expression. Blood. 87(2):666-73.

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Specifications

pDRIVE bearing human B29 promoter - LacZ, SEAP or Lucia

Gene Promoter: Immunoglobulin Beta

Specificity: B cells

Backbone: pDRIVE, pDRIVE5-SEAP or pDRIVE5-Lucia

Selection: Zeocin™

pDRIVE bearing mouse B29 promoter - LacZ, SEAP or Lucia

Gene: Immunoglobulin Beta

Specificity: B cells

Backbone: pDRIVE, pDRIVE5-SEAP or pDRIVE5-Lucia

Selection: Zeocin™

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pDRIVE contents

  • 20 µg of lyophilized DNA
  • 1 ml of Zeocin™ (100 mg/ml)

room temperature Product is shipped at room temperature

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