pDRIVE-B29
| Product | Unit size | Cat. code | Docs. | Qty. | Price | |
|---|---|---|---|---|---|---|
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pDRIVE-hB29 pDRIVE bearing human B29 promoter - LacZ |
Show product |
20 µg |
pdrive-hb29
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pDRIVE5SEAP-hB29 pDRIVE bearing human B29 promoter - SEAP |
Show product |
20 µg |
pdrive5s-hb29
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pDRIVE5Lucia-hB29 pDRIVE bearing human B29 promoter - Lucia |
Show product |
20 µg |
pdrive5lc-hb29
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pDRIVE-mB29 pDRIVE bearing mouse B29 promoter - LacZ |
Show product |
20 µg |
pdrive-mb29
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pDRIVE5SEAP-mB29 pDRIVE bearing mouse B29 promoter - SEAP |
Show product |
20 µg |
pdrive5s-mb29
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pDRIVE5Lucia-mB29 pDRIVE bearing mouse B29 promoter - Lucia |
Show product |
20 µg |
pdrive5lc-mb29
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B29 promoter (B cells) in pDRIVE expression plasmid
B29 (Igbeta) is a B-cell-specific member of the immunoglobulin gene superfamily that is expressed throughout B-cell development.
The product of the B29 gene is an essential component of the B cell receptor and plays a critical role in B cell development.
The B29 gene lacks either a TATA or a CAAT box and transcription is initiated at multiple sites [1].
The minimal promoter of the human B29 gene is contained within a <200-bp region 5' of these multiple start sites [2].
This minimal promoter exhibits B-cell-specific activity and contains SP1, ETS, OCT, and IKAROS/LYF-1 transcription factor motifs [3].
References:
1. Hermanson GG. et al. 1989. Immunoglobulin enhancer and promoter motifs 5' of the B29 B-cell-specific gene. Proc Natl Acad Sci U S A 86(19):7341-5.
2. Omori SA. & Wall R. 1993. Multiple motifs regulate the B-cell-specific promoter of the B29 gene. Proc Natl Acad Sci USA 90(24):11723-7.
3. Thompson AA. et al., 1996. The promoter and 5' flanking sequences controlling human B29 gene expression. Blood. 87(2):666-73.
Specifications
pDRIVE bearing human B29 promoter - LacZ, SEAP or Lucia
Gene Promoter: Immunoglobulin Beta
Specificity: B cells
Backbone: pDRIVE, pDRIVE5-SEAP or pDRIVE5-Lucia
Selection: Zeocin™
pDRIVE bearing mouse B29 promoter - LacZ, SEAP or Lucia
Gene: Immunoglobulin Beta
Specificity: B cells
Backbone: pDRIVE, pDRIVE5-SEAP or pDRIVE5-Lucia
Selection: Zeocin™
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pDRIVE contents
- 20 µg of lyophilized DNA
- 1 ml of Zeocin™ (100 mg/ml)
Product is shipped at room temperature