Innate immunity / PRR

RIG-I-like receptors (RLRs) constitute a family of cytoplasmic RNA helicases that are critical for...
Innate immunity / PRR

Toll-like receptors (TLRs) are the best studied pattern recognition receptors (PRRs) and their...
Innate immunity / PRR / STING

Cytosolic DNA is well-known to induce the production of type I interferons (IFNs) through the STING...
COVID-19

The global vaccine effort in response to the COVID-19 pandemic is unprecedented in terms of both...
Innate immunity

Toll-like receptors (TLRs) play a pivotal role in the initiation of prompt innate immune defenses...
Innate immunity / Inflammasome

Regulated cell death (RCD) is a lethal process taking place in the context of stressful stimuli (e.g...
COVID-19

Learn more about the growing evidence that re-infection by SARS-CoV-2 can occur, with protective...
COVID-19

Currently, there is very limited knowledge of the host immune response to SARS-CoV-2. However, based...
COVID-19

Currently, there are no specific therapies approved for the treatment of coronavirus disease 2019...
COVID-19

COVID-19 is a pandemic that threatens global health. Its causative agent, SARS-CoV-2, a novel β...
Innate immunity

Toll-like receptors (TLRs) play a pivotal role in the initiation of anti-infectious immune responses...
Innate immunity / PRR / Inflammasome

NLRP3 is the best-described inflammasome sensor and an attractive drug target.
Innate immunity / PRR

The development of immune checkpoint inhibitors (ICIs) has revolutionized cancer immunotherapy...
Antibodies

Immune Checkpoint Anti-human Antibodies, ADCC Reporter Cell-Based Assay, Antibody Engineering
Innate immunity / PRR

The aryl hydrocarbon receptor (AhR) is a ligand-dependent transcriptional factor widely expressed...
Antibodies / Vaccine & immunoglobulin

Antibodies are immunoglobulin (Ig) molecules made up of 2 large heavy chains (~55 kDa each) and 2...