STING / Innate immunity / Vaccination
Adjuvants enhance and direct the adaptive immune response to vaccine antigens through various...
Innate immunity
The innate immune system is an evolutionarily conserved system acting as a first-line of defense...
Inflammasome / Innate immunity
The nucleotide-binding oligomerization domain-like receptor (NLR) family of proteins is involved in...
Products
Luciferases encompass a wide range of enzymes used for bioluminescence, the emission of light...
Innate immunity / PRR
The cytosolic NOD-Like Receptors (NLRs, also known as CATERPILLERs, NODs or NALP/PAN/PYPAFs) are...
STING / Innate immunity / PRR
The innate immune system provides the first line of defense against infectious pathogens and serves...
Innate immunity / PRR
The Third International DAMPs and Alarmins Symposium was held in Pittsburgh, USA in 2008. The aim of...
Products
The design of siRNAs and short hairpin siRNAs (shRNAs) remains an empirical process since the...
Innate immunity / PRR
Dectin-1 is a recently discovered pattern-recognition receptor that plays an important role in...
Innate immunity / PRR
Toll-like receptor 9 (TLR9) senses unmethylated CpG dinucleotides, a hallmark of microbial DNA, that...
Innate immunity / IFN responses
RNA interference (RNAi) has become a powerful tool to uncover gene function and is evolving as a new...
Innate immunity / PRR / IFN responses
Viral infections induce a strong innate immune response characterized by the rapid production of...
Innate immunity / PRR
Bacterial lipopolysaccharide (LPS) is the major structural component of the outer wall of all Gram...
PRR / Innate immunity
TLR7 and TLR8 are phylogenetically and structurally related. TLR7 is predominantly expressed in lung...
Products
RNA interference (RNAi) is one of the most exciting discoveries of the past decade in functional...
Innate immunity / PRR
Toll-like receptor 9 (TLR9) recognizes unmethylated bacterial CpG DNA and initiates a signaling...
