CpG-free Luc::Sh

Synthetic reporter / resistance fusion gene in expression plasmid

InvivoGen has engineered a fusion between the firefly luciferase (Luc) and the Sh ble genes. The firefly Luc gene is a highly sensitive reporter gene and thus is ideal for detecting low-level gene expression.

The Sh ble gene confers Zeocin™ resistance. Both genes have been modified and contain no CpGs.

The Luc::Sh fusion gene exhibits a higher luciferase activity and enables a better and faster selection of Zeocin™ resistant clones.

The synthetic Luc::Sh fusion gene is provided in the expression plasmid pSelect-zeo which is selectable with Zeocin™ in mammalian and E.coli cells.