pFUSEN-Lucia-mG2aFc
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pFUSEN-Lucia-mG2aFc Lucia luciferase-tagged Fc-fusion protein expression plasmid - Mouse IgG2a |
Show product |
20 µg |
pfcn-lcmg2a
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Production of Lucia luciferase-tagged IgG2a-Fc fusion proteins
pFUSEN-Lucia-mG2aFc is a cloning plasmid for the generation of a Lucia luciferase-tagged Fc-fusion protein expressing the Fc region (CH2 and CH3 domains) of the murine IgG2a heavy chain and the hinge region fused to the N-terminus of a protein of interest.
Lucia luciferase is a secreted luciferase reporter protein with advantageous characteristics when associated with Fc-fusion proteins.
It possesses superior carrier ability for excellent secretion of the chimeric protein. It provides a simple means to screen for recombinant clones and it minimally affects the activity of the protein of interest.
Mouse IgG2a-Fc is the murine equivalent of human IgG1-Fc. It has moderate to high affinity for FcγRs and complement receptors, inducing strong ADCC and CDC.
Back to the topSpecifications
Isotype : IgG2A mouse
Effector Activities : ADCC+++, CDC +++
Selectable with Zeocin™ in E. coli and mammalian cells.
For transient or stable transfection.
These products are covered by a Limited Use License (See Terms and Conditions).
Back to the toppFUSEN Contents
- 20 µg of lyophilized DNA
- 1 ml of Zeocin™ (100 mg/ml)
Product is shipped at room temperature
