pFUSEN-Lucia-mG2aFc
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Cat.code:
pfcn-lcmg2a
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ABOUT
Production of Lucia luciferase-tagged IgG2a-Fc fusion proteins
pFUSEN-Lucia-mG2aFc is a cloning plasmid for the generation of a Lucia® luciferase-tagged Fc-fusion protein expressing the Fc region (CH2 and CH3 domains) of the murine IgG2a heavy chain and the hinge region fused to the N-terminus of a protein of interest.
Lucia® luciferase is a secreted luciferase reporter protein with advantageous characteristics when associated with Fc-fusion proteins.
It possesses superior carrier ability for excellent secretion of the chimeric protein. It provides a simple means to screen for recombinant clones and it minimally affects the activity of the protein of interest.
Mouse IgG2a-Fc is the murine equivalent of human IgG1-Fc. It has moderate to high affinity for FcγRs and complement receptors, inducing strong ADCC and CDC.
Disclaimer: This product is covered by a Limited Use License (See Terms and Conditions).
Lucia® is a trademark of InvivoGen registered with the United States Patent and Trademark Office and foreign equivalents.
All InvivoGen products are for internal research use only, and not for human or veterinary use.
SPECIFICATIONS
Specifications
Fc-fusion protein generation
Plasmid construct is confirmed by restriction analysis and full-length open reading frame (ORF) sequencing.
CONTENTS
Contents
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Product:pFUSEN-Lucia-mG2aFc
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Cat code:pfcn-lcmg2a
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Quantity:20 µg
1 ml of Zeocin® (100 mg/ml)
Shipping & Storage
- Shipping method: Room temperature
- -20°C
- Avoid repeated freeze-thaw cycles
Storage:
Caution:
DOCUMENTS
Documents
Technical Data Sheet
Safety Data Sheet
Certificate of analysis
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