pFUSEN-hG1Fc

Fc-fusion protein expression plasmid - Human IgG1

ABOUT

pFUSEN-hG1Fc is a cloning plasmid for the generation of a Fc-fusion protein expressing the Fc region (CH2 and CH3 domains) of the human IgG1 heavy chain and the hinge region fused to the N-terminus of a protein of interest.

Human IgG1-Fc exhibits moderate to high affinity for FcγRs and complement receptors, thus triggering strong ADCC and CDC, respectively.
Currently, all Fc-fusions licensed for clinical use contain the IgG1-Fc domain.

All products are for research use only, and not for human or veterinary use.

SPECIFICATIONS

Specifications

Plasmid backbone
pFUSE
Gene promoter
Human EF1α/HTLV hybrid promoter
Appearance (form)
Lyophilized
Reconstitution buffer
Endotoxin-free water (not provided).
Tested applications

in vitro transfection

Quality control

Plasmid construct is confirmed by restriction analysis and full-length open reading frame (ORF) sequencing.

CONTENTS

Contents

  • Product: 
    pFUSEN-hG1Fc
  • Cat code: 
    pfcn-hg1
  • Quantity: 
    20 µg
Includes:

1 ml of Zeocin™ (100 mg/ml)

Shipping & Storage

  • Shipping method:  Room temperature
  • Storage:

    • Upon receipt, store at -20°C.
    Stability: Reconstituted product is stable at least for 1 year at -20 °C

DOCUMENTS

Documents

pFUSEN-hG1Fc

Technical Data Sheet

Safety Data Sheet

Certificate of analysis

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CUSTOMER SERVICE & TECHNICAL SUPPORT

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