pBOOST2-wthIRF1
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pBOOST2 Human Wild-type IRF-1
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Cat.code:
pbst2-wthirf1
- Documents
ABOUT
Genetic adjuvants for DNA vaccines with wild-type IRF1 genes | Increase Th2 response
pBOOST2-wtIRF1 plasmids express the human or murine wild-type interferon regulatory factor 1 (IRF-1) gene. IRF-1 has been described to primarily increase Th2 antibody responses [1].
Following intramuscular or gene gun injections of DNA vaccines, IRF-1 can increase the titers of antibodies up to 10-fold.
pBOOST2-wtIRF1 plasmids express the transgene under the control of the strong and ubiquitous EF-1α/HTLV composite promoter and are selectable in E. coli with Zeocin™.
Reference:
1. Sasaki S. et al., 2002. Regulation of DNA-raised immune responses by cotransfected interferon regulatory factors. J Virol.76(13):6652-9.
All products are for research use only, and not for human or veterinary use.
SPECIFICATIONS
Specifications
in vitro transfection
Plasmid construct has been confirmed by restriction analysis and sequencing.
CONTENTS
Contents
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Product:pBOOST2-wthIRF1
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Cat code:pbst2-wthirf1
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Quantity:20 µg
1 ml of Zeocin™ (100 mg/ml)
Shipping & Storage
- Shipping method: Room temperature
- -20°C
- Avoid repeated freeze-thaw cycles
Storage:
Caution:
DOCUMENTS
Documents
Technical Data Sheet
Safety Data Sheet
Plasmid Sequence
Certificate of analysis
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