Anti-hCD20-mIgA

Human CD20 (Rituximab) antibody - Murine IgA

ABOUT

Monoclonal mouse IgA antibody against human CD20

Anti-hCD20-mIgA features the constant region of the mouse IgA isotype and the variable region of rituximab.

Rituximab is a mouse/human chimeric monoclonal antibody that targets the CD20 antigen found on the surface of malignant and normal B lymphocytes.

Binding of rituximab to CD20 results in cell destruction through different mechanisms including direct signaling of apoptosis, complement activation and cell-mediated cytotoxicity.

Rituximab has been approved by the FDA for the treatment of various lymphoid malignancies, including B-cell non-Hodgkin's lymphoma and B-cell chronic lymphocytic leukaemia.

Anti-hCD20-mIgA was generated by recombinant DNA technology.

It has been produced in CHO cells and purified by affinity chromatography with protein L. 

All products are for research use only, and not for human or veterinary use.

SPECIFICATIONS

Specifications

Species
Mouse
Isotype
IgA
kappa
Source
CHO cells
Purification
Protein L
Reconstitution buffer
Endotoxin-free water (not provided).

CONTENTS

Contents

  • Product: 
    Anti-hCD20-mIgA
  • Cat code: 
    hcd20-mab11
  • Quantity: 
    Custom size

Shipping & Storage

  • Shipping method:  Room temperature

    • Storage:

    • Upon receipt, store at -20°C.

    Caution:

    • Avoid repeated freeze-thaw cycles

DOCUMENTS

Documents

Anti-hCD20-mIgA

Technical Data Sheet

Safety Data Sheet

Certificate of analysis

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Citations

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