β-Gal / β-Galactosidase antibody for ADC (isotype control)

Human IgG1 - For antibody-drug conjugation

ABOUT

Monoclonal human IgG1 antibody against β-galactosidase for antibody-drug conjugation

InvivoGen provides Anti-β-Gal-hIgG1*, a monoclonal antibody (mAb) specifically developed for the generation of control antibody-drug conjugates (ADCs). This mAb features:

  • the variable region of a murine mAb which specifically targets the E. coli β-galactosidase (β-Gal),
  • a human IgG1 constant region that displays high effector functions, including antibody-dependent cell-mediated cytotoxicity (ADCC), and complement-dependent cytotoxicity (CDC).

InvivoGen's Anti-β-Gal-hIgG1* has been generated by recombinant DNA technology, produced in CHO cells, and purified by affinity chromatography.

 

Key features of Anti-β-Gal-hIgG1*:

  • No binding to any other antigen than β-Gal, as verified by ELISA, flow cytometry, and ADC-based cellular assays
  • Human IgG1 constant region for high effector functions
  • The absence of bacterial contamination has been confirmed

 

Application for Anti-β-Gal-hIgG1*:

  • Negative control for ADC-based assays
     

InvivoGen offers Anti-HER2-IgG1 and Anti-TROP2-hIgG1 specific mAbs, as well as conjugatable PRR ligands for building immunostimulatory ADCs.
You may choose from TLR7 and STING agonists:
Conjugatable TLR7 agonists: TL7-887 and TL7-975
Conjugatable STING agonists: STG-982 and STG-968

 

Learn more about bioconjugation

 

All products are for internal research use only, and not for human or veterinary use.

SPECIFICATIONS

Specifications

Applications

Flow cytometry, ELISA, Antibody-drug conjugation

Isotype
hIgG1
Source
CHO cells
Purification
Protein A
Formulation buffer

0.2 μm filtered solution in 150 mM sodium chloride, 20 mM sodium phosphate buffer with 5% saccharose

Reconstitution buffer
Sterile Water
Tested applications

Flow cytometry, ELISA, Antibody-drug conjugation

Quality control

Each lot is functionally tested and validated. 

CONTENTS

Contents

  • Product: 
    Anti-β-Gal-hIgG1*
  • Cat code: 
    bgal-mab1-1
  • Quantity: 
    1 mg

Shipping & Storage

    Caution:

    • Avoid repeated freeze-thaw cycles

DOCUMENTS

Documents

Anti-β-Gal-hIgG1*

Technical Data Sheet

Validation Data Sheet

Safety Data Sheet

Certificate of analysis

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CUSTOMER SERVICE & TECHNICAL SUPPORT

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