Anti-β-Gal-hIgG1*
-
Cat.code:
bgal-mab1-1
- Documents
ABOUT
Monoclonal human IgG1 antibody against β-galactosidase for antibody-drug conjugation
InvivoGen provides Anti-β-Gal-hIgG1*, a monoclonal antibody (mAb) specifically developed for the generation of control antibody-drug conjugates (ADCs). This mAb features:
- the variable region of a murine mAb which specifically targets the E. coli β-galactosidase (β-Gal),
- a human IgG1 constant region that displays high effector functions, including antibody-dependent cell-mediated cytotoxicity (ADCC), and complement-dependent cytotoxicity (CDC).
InvivoGen's Anti-β-Gal-hIgG1* has been generated by recombinant DNA technology, produced in CHO cells, and purified by affinity chromatography.
Key features of Anti-β-Gal-hIgG1*:
- No binding to any other antigen than β-Gal, as verified by ELISA, flow cytometry, and ADC-based cellular assays
- Human IgG1 constant region for high effector functions
- The absence of bacterial contamination has been confirmed
Application for Anti-β-Gal-hIgG1*:
- Negative control for ADC-based assays
InvivoGen offers Anti-HER2-IgG1 and Anti-TROP2-hIgG1 specific mAbs, as well as conjugatable PRR ligands for building immunostimulatory ADCs.
You may choose from TLR7 and STING agonists:
- Conjugatable TLR7 agonists: TL7-887 and TL7-975
- Conjugatable STING agonists: STG-982 and STG-968
Learn more about bioconjugation
All products are for internal research use only, and not for human or veterinary use.
SPECIFICATIONS
Specifications
Flow cytometry, ELISA, Antibody-drug conjugation
0.2 μm filtered solution in 150 mM sodium chloride, 20 mM sodium phosphate buffer with 5% saccharose
Flow cytometry, ELISA, Antibody-drug conjugation
Each lot is functionally tested and validated.
CONTENTS
Contents
-
Product:Anti-β-Gal-hIgG1*
-
Cat code:bgal-mab1-1
-
Quantity:1 mg
Shipping & Storage
- Avoid repeated freeze-thaw cycles
Caution:
DOCUMENTS
Documents
Technical Data Sheet
Validation Data Sheet
Safety Data Sheet
Certificate of analysis
Need a CoA ?