Poly(I:C) (HMW) Rhodamine - TLR3 Agonist

Rhodamine-labeled poly(I:C) (HMW)

ABOUT

Rhodamine-labeled poly(I:C) (HMW)

Poly(I:C) Rhodamine was chemically labeled by covalent coupling of a rhodamine probe containing a reactive alkylating group. This confers fluorescent properties to poly(I:C) (HMW) whilst retaining TLR3 recognition properties.

Polyinosinic-polycytidylic acid (poly(I:C)) is a synthetic analog of double stranded RNA (dsRNA), a molecular pattern associated with viral infection.

Both natural and synthetic dsRNAs are known to induce type I interferons (IFN) and other cytokines production.

Poly(I:C) is recognized by Toll-like receptor 3 (TLR3).

All products are for research use only, and not for human or veterinary use.

SPECIFICATIONS

Specifications

Source
Synthetic
Working concentration

10 ng/ml - 10 μg/ml

Appearance (form)
Lyophilized powder
Appearance (color)
Pink
Tested applications

Cellular assays

Quality control

Human TLR3 (hTLR3) activity tested using HEK-Blue™ hTLR3 cells. Rhodamine fluorescence evaluated on RAW-Blue™ cells using FACS analysis.

Additional information

Spectral Properties of Rhodamine

  • Excitation λ max: 546 nm
  • Emission λ max: 576 nm

CONTENTS

Contents

  • Product: 
    Poly(I:C) (HMW) Rhodamine
  • Cat code: 
    tlrl-picr
  • Quantity: 
    10 µg
Includes:

1.5 ml sterile endotoxin-free water

Shipping & Storage

  • Shipping method:  Room temperature

    • Storage:

    • -20°C
    Stability: Resuspended product is stable for 3 months at -20°C.

    Caution:

    • Avoid repeated freeze-thaw cycles
    • Protect from light

DOCUMENTS

Documents

Poly(I:C) (HMW) Rhodamine

Technical Data Sheet

Safety Data Sheet

Certificate of analysis

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Citations

CUSTOMER SERVICE & TECHNICAL SUPPORT

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