pFUSE-hIgG2-Fc

Fc-fusion protein expression plasmid - Human IgG2

ABOUT

Fc-fusion protein expression plasmid - Human IgG2

pFUSE-hIgG2-Fc1 is a cloning plasmid for the generation of a Fc-fusion protein expressing the Fc region (CH2 and CH3 domains) of the human IgG2 heavy chain and the hinge region.

The hinge serves as a flexible spacer between the two parts of the Fc-fusion protein, allowing each part of the molecule to function independently.

Human IgG2 dispays low ADCC and CDC.

pFUSE-hIgG2-Fc2 additionally features the IL2 signal sequence for the generation of Fc-Fusion proteins derived from proteins that are not naturally secreted

All products are for research use only, and not for human or veterinary use.

SPECIFICATIONS

Specifications

Species
Human
Tag
Fc, C-ter
Plasmid backbone
pFUSE
Antibiotic resistance
Zeocin®
Gene promoter
Human EF1α/HTLV hybrid promoter
Reconstitution buffer
Endotoxin-free water (not provided)
Tested applications

in vitro transfection

Quality control

Plasmid construct is confirmed by restriction analysis and full-length open reading frame (ORF) sequencing.

CONTENTS

Contents

  • Product: 
    pFUSE-hIgG2-Fc1
  • Cat code: 
    pfuse-hfc1
  • Quantity: 
    20 µg
Includes:

1 ml of Zeocin® (100 mg/ml)

Shipping & Storage

  • Shipping method:  Room temperature
  • Storage:

    • -20°C
    Stability: Stable up to 1 year when stored at -20°C

DOCUMENTS

Documents

pFUSE-hIgG2-Fc1

Technical Data Sheet

Safety Data Sheet

Plasmid Sequence

Certificate of analysis

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CUSTOMER SERVICE & TECHNICAL SUPPORT

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