Invivogen
Menu

pDRIVE-Mb

Product Unit size Cat. code Docs. Qty. Price

pDRIVE-hMb

pDRIVE bearing human Mb promoter - LacZ

Show product

20 µg

pdrive-hmb
+-
$554

pDRIVE5SEAP-hMb

pDRIVE bearing human Mb promoter - SEAP

Show product

20 µg

pdrive5s-hmb
+-
$554

pDRIVE5Lucia-hMb

pDRIVE bearing human Mb promoter - Lucia

Show product

20 µg

pdrive5lc-hmb
+-
$554

pDRIVE-mMb

pDRIVE bearing mouse Mb promoter - LacZ

Show product

20 µg

pdrive-mmb
+-
$554

pDRIVE5SEAP-mMb

pDRIVE bearing mouse Mb promoter - SEAP

Show product

20 µg

pdrive5s-mmb
+-
$554

pDRIVE5Lucia-mMb

pDRIVE bearing mouse Mb promoter - Lucia

Show product

20 µg

pdrive5lc-mmb
+-
$554

Mb promoter (Muscle) in pDRIVE expression plasmid

Myoglobin is a cytoplasmic hemoprotein that binds molecular oxygen to facilitate its diffusion from the vascular system to the muscle mitochondria.

Myoglobin is found only in muscle, predominantly in cardiac and skeletal myocytes.

he myoglobin promoter can drive the expression of a transgene in multinucleated myotubes but not in  mononucleated and undifferentiated cells [1].

This capacity is conferred by a small segment of the 5’ flanking region extending from nucleotides -357 to +55 relative to the transcriptional start site [2].

 

References:

1. Devlin BH. et al. 1989. Identification of a muscle-specific enhancer within the 5’-flanking region of the human myoglobin gene. J Biol Chem 264(23):13896-13901.
2. Yan Z. et al. 2001. Regulatory elements governing transcription in specialized myofiber subtypes. J Biol Chem 276(20):17361-17366.

Back to the top

Specifications

pDRIVE bearing human Mb promoter - LacZ, SEAP or Lucia

Gene Promoter: Myoglobin

Specificity: Muscle

Backbone: pDRIVE, pDRIVE5-SEAP or pDRIVE5-Lucia

Selection: Zeocin™

pDRIVE bearing mouse Mb promoter - LacZ, SEAP or Lucia

Gene: Myoglobin

Specificity: Muscle

Backbone: pDRIVE, pDRIVE5-SEAP or pDRIVE5-Lucia

Selection: Zeocin™

Back to the top

pDRIVE contents

  • 20 µg of lyophilized DNA
  • 1 ml of Zeocin™ (100 mg/ml)

room temperature Product is shipped at room temperature

Back to the top
Customer Service
& Technical Support
Shopping cart is empty