pCpGfree-OVA

OVA-expressing CpG-free plasmid

pCpGfree-OVA is a plasmid completely devoid of CpG dinucleotides. It expresses a synthetic OVA gene, a CpG-free allele of the ovalbumin (OVA) gene constructed by chemical synthesis.

This plasmid is designed for DNA immunization experiments in animal models. This plasmid possesses dual functions; it can be used as a DNA vaccine carrier for antigen presentation, and as an immune-stimulative adjuvant [1].

Reference:

1. Miura N. et al., 2015. A KALA-modified lipid nanoparticle containing CpG-free plasmid DNA as a potential DNA vaccine carrier for antigen presentation and as an immune-stimulative adjuvant. Nucleic Acids Res. 43(3):1317-31.