CpG-free HSV1-tk::Sh
| Product | Unit size | Cat. code | Docs. | Qty. | Price | |
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pSELECT-zeo-HSV1tkSh Synthetic HSV1 thymidine kinase - Zeocin™ resistance fusion gene |
Show product |
20 µg |
psetz-hsv1tksh
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Synthetic cytotoxic / resistance fusion gene in expression plasmid
Suicide genes code for enzymes that convert non-toxic compounds (prodrugs) into toxic products.
The thymidine kinase (tk) gene from Herpes simplex virus type 1 (HSV1) codes for thymidine kinase, an enzyme able to convert nucleoside analogs such as ganciclovir into cytotoxic molecules.
InvivoGen has engineered a synthetic CpG-free fusion gene between the HSV1-tk gene and the Sh ble gene conferring Zeocin™ resistance.
This fusion gene enables a better and faster selection of Zeocin-resistant clones.
The CpG-free HSV1-tk::Sh fusion gene is provided in the expression plasmid pSelect-zeo which is selectable with Zeocin™ in both mammalian and E.coli cells.
Back to the topSpecifications
Gene: CpG-free HSV1-tk::Sh
Description: Synthetic HSV1 thymidine kinase - Zeocin™ resistance fusion gene
Backbone: pSELECT-zeo
Selection: Zeocin™
372 CpG in native gene
Back to the topContents
- 20 µg of lyophilized DNA
- 1 ml of Zeocin™ (100 mg/ml)
Product is shipped at room temperature