PGLYRP1
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pUNO1-hPGLYRP1 pUNO1 bearing the human PGLYRP1 (PGRPS) gene |
Show product |
20 µg |
puno1-hpglyrp1
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pUNO1-mPGLYRP1 pUNO1 bearing the mouse PGLYRP1 (PGRPS) gene |
Show product |
20 µg |
puno1-mpglyrp1
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Expression-ready ORF Clones
Alias : PGRPS, TAG7
Peptidoglycan recognition protein 1.
Peptidoglycan Recognition Protein, Short.
Peptidoglycan recognition proteins (PGRPs) are pattern recognition molecules that are conserved from insects to mammals and recognize bacteria and their unique cell wall component, peptidoglycan (PGN) [1]. However, the consequences of this recognition are unknown, except in insects where PGRPs trigger the expression of antimicrobial peptides [2]. Four mammalian PGRPs have been identified, PGRP-L, -S, -Ialpha, and -Ibeta, that are selectively expressed in different organs and have little homology outside the PGRP domains [3]. This diversity suggests that binding of PGN to each PGRP may produce a different biological effect.
1. Dziarski R., 2004. Peptidoglycan recognition proteins (PGRPs). Mol Immunol. 40(12):877-86.
2. Takehana A. et al., 2002. Overexpression of a pattern-recognition receptor, peptidoglycan-recognition protein-LE, activates imd/relish-mediated antibacterial defense and the prophenoloxidase cascade in Drosophila larvae. Proc Natl Acad Sci U S A.99(21):13705-10.
3. Liu C. et al., 2001. Peptidoglycan recognition proteins: a novel family of four human innate immunity pattern recognition molecules.J Biol Chem. 276(37):34686-94.
Specifications
Human PGLYRP1 (pUNO1-hPGLYRP1)
Genbank : NM_005091.2
ORF size : 591 bp
Subclone : AgeI - NheI
Mouse PGLYRP1 (pUNO1-mPGLYRP1)
Genbank : NM_009402.2
ORF size : 549 bp
Subclone : AgeI - NheI
pUNO1 Contents
- 20 µg of lyophilized DNA
- 2 x 1 ml blasticidin at 10 mg/ml
Product is shipped at room temperature.
Lyophilized DNA should be stored at -20°C. Upon receipt, store blasticidin at 4°C or -20°C.
Resuspended DNA should be stored at -20°C and is stable for up to 1 year.
Blasticidin is a harmful compound. Refer to the safety data sheet for handling instructions.