
pUNO1-hMBL2
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Cat.code:
puno1-hmbl2
- Documents
Expression-ready ORF Clones
Alias : COLEC1, MBL, MBP1
Mannose binding lectin 2.
Mannose-binding lectin (protein C) 2, soluble.
Mannose-binding lectin (MBL), also called mannose-binding protein (MBP) is a member of the collectin family of proteins in which collagen structures are associated with carbohydrate-recognizing lectin domains [1]. MBL is a serum protein that binds a large variety of sugar moieties expressed by bacteria, viruses, protozoa and helminths through a pattern-recognition mode of detection [2]. MBL can mediate phagocytosis of microorganisms and induce inflammatory responses. MBL can also activate the complement system via MBL-associated serine proteases (MASPs). MBL is encoded by a single human gene, mbl2 (mbl1 is a pseudogene) and by two mouse genes, mbl1 and mbl2 [3].
1. Holmskov U. et al., 2003. Collections and ficolins: humoral lectins of the innate immune defense. Annu Rev Immunol. 21:547-78..
2. Jack DL. & Turner MW., 2003. Anti-microbial activities of mannose-binding lectin. Biochem Soc Trans. 31(Pt 4):753-7.
3. Sastry, R. et al., 1995. Characterization of murine mannose-binding protein genes Mbl1 and Mbl2 reveals features common to other collectin genes. Mamm. Genome 6: 103-110.
Specifications
Human MBL2 (pUNO1-hMBL2)
Genbank : AY826184.1ORF size : 747 bp
Subclone : BspLU11I - NheI
Mouse MBL2 (pUNO1-mMBL2)
Genbank : NM_010776.1ORF size : 735 bp
Subclone : BspLU11I - NheI
Contents
- 20 µg of lyophilized DNA
- 2 x 1 ml blasticidin at 10 mg/ml
Product is shipped at room temperature.
Lyophilized DNA should be stored at -20°C. Upon receipt, store blasticidin at 4°C or -20°C.
Resuspended DNA should be stored at -20°C and is stable for up to 1 year.
Blasticidin is a harmful compound. Refer to the safety data sheet for handling instructions.
DOCUMENTS
Documents
Technical Data Sheet
Safety Data Sheet
Plasmid Map and Sequence
Plasmid Sequence
Certificate of analysis
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