pFUSE-hIgG4-Fc
| Product | Unit size | Cat. code | Docs. | Qty. | Price | |
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pFUSE-hIgG4-Fc1 Fc-fusion protein expression plasmid - Human IgG4 |
Show product |
20 µg |
pfuse-hg40fc1
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pFUSE-hIgG4-Fc2 Fc-fusion protein expression plasmid - Human IgG4 with IL2ss |
Show product |
20 µg |
pfuse-hg40fc2
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Fc-fusion protein expression plasmid - Human IgG4
pFUSE-hIgG4-Fc1 is a cloning plasmid for the generation of a Fc-fusion protein expressing the Fc region (CH2 and CH3 domains) of the human IgG4 heavy chain and the hinge region.
The hinge serves as a flexible spacer between the two parts of the Fc-fusion protein, allowing each part of the molecule to function independently.
Human IgG4 displays low ADCC and CDC.
pFUSE-hIgG4-Fc2 additionally features the IL2 signal sequence for the generation of Fc-Fusion proteins derived from proteins that are not naturally secreted.
Back to the topSpecifications
Isotype : IgG4 human
Effector Activities : ADCC+/-, CDC-
Protein A binding: ++++
Protein G binding: ++++
Both plasmids are selectable with Zeocin™.
Back to the toppFUSE Contents
- 20 µg of lyophilized DNA
- 1 ml of Zeocin® (100 mg/ml)
Product is shipped at room temperature