pFUSE-hIgG1-Fc

Fc-fusion protein expression plasmid - Human IgG1

ABOUT

Fc-fusion protein expression plasmid - Human IgG1

pFUSE-hIgG1-Fc1 is a cloning plasmid for the generation of a Fc-fusion protein expressing the Fc region (CH2 and CH3 domains) of the human IgG1 heavy chain and the hinge region.

The hinge serves as a flexible spacer between the two parts of the Fc-fusion protein, allowing each part of the molecule to function independently.

Human IgG1 displays high ADCC and CDC, and is the most suitable for therapeutic use against pathogens and cancer cells.

pFUSE-hIgG1-Fc2 additionally features the IL2 signal sequence for the generation of Fc-Fusion proteins derived from proteins that are not naturally secreted.

All products are for research use only, and not for human or veterinary use.

SPECIFICATIONS

Specifications

Applications

 Fc-fusion protein generation

Plasmid backbone
pFUSE
Antibiotic resistance
Zeocin®
Gene promoter
Human EF1α/HTLV hybrid promoter
Signal sequence
w or w/o human IL2 signal sequence
Purification
Ion-exchange chromatography
Appearance (form)
Lyophilized
Reconstitution buffer
Endotoxin-free water (not provided)
Tested applications

In vitro transfection

Quality control

Plasmid construct has been confirmed by restriction analysis and sequencing.

CONTENTS

Contents

  • Product: 
    pFUSE-hIgG1-Fc1
  • Cat code: 
    pfuse-hg1fc1
  • Quantity: 
    20 µg
Includes:

1 ml of Zeocin® (100 mg/ml)

Shipping & Storage

  • Shipping method:  Room temperature
  • Storage:

    • -20°C

    Caution:

    • Avoid repeated freeze-thaw cycles

DOCUMENTS

Documents

pFUSE-hIgG1-Fc1

Technical Data Sheet

Safety Data Sheet

Plasmid Sequence

Certificate of analysis

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CUSTOMER SERVICE & TECHNICAL SUPPORT

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