Zymosan
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Cat.code:
tlrl-zyn
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ABOUT
Cell wall preparation of S. cerevisiae
Zymosan, an insoluble preparation of cell wall from Saccharomyces cerevisiae, activates macrophages via TLR2.
TLR2 cooperates with TLR6 and CD14 in response to zymosan [1].
Zymosan is also recognized by Dectin-1, a phagocytic receptor expressed on macrophages and dendritic cells, which collaborates with TLR2 and TLR6 enhancing the immune responses triggered by the recognition of Zymosan by each receptor [2].
References:
1. Ozinsky A. et al., 2000. The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors. PNAS. 97(25):13766-71.
2. Gantner BN. et al., 2003. Collaborative induction of inflammatory responses by dectin-1 and Toll-like receptor 2. J Exp Med. 197(9):1107-17.
All products are for research use only, and not for human or veterinary use.
SPECIFICATIONS
Specifications
1 - 10 μg/ml
Insoluble
Each lot is functionally tested and validated
CONTENTS
Contents
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Product:Zymosan
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Cat code:tlrl-zyn
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Quantity:100 mg
10 ml sterile endotoxin-free water
Shipping & Storage
- Shipping method: Room temperature
- 4°C or -20°C
- Avoid repeated freeze-thaw cycles
Storage:
Caution:
DOCUMENTS
Documents
Technical Data Sheet
Safety Data Sheet
Certificate of analysis
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