Poly(I:C) (LMW) Rhodamine
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Cat.code:
tlrl-piwr
- Documents
ABOUT
Rhodamine-labeled poly(I:C) (LMW)
Poly(I:C) Rhodamine was chemically labeled by covalent coupling of a rhodamine probe containing a reactive alkylating group. This confers fluorescent properties to poly(I:C) (LMW) whilst retaining TLR3 recognition properties.
Polyinosinic-polycytidylic acid (poly(I:C)) is a synthetic analog of double stranded RNA (dsRNA), a molecular pattern associated with viral infection.
Both natural and synthetic dsRNAs are known to induce type I interferons (IFN) and other cytokines production.
Poly(I:C) is recognized by Toll-like receptor 3 (TLR3).
InvivoGen provides poly(I:C) with a high molecular weight (HMW) or a low molecular weight (LMW) that might activate the immune system differently.
All products are for internal research use only, and not for human or veterinary use.
SPECIFICATIONS
Specifications
TLR3
100 ng - 10 μg/ml
100 µg/ml in water
The absence of bacterial contamination (e.g. lipoproteins and endotoxins) is confirmed using HEK-Blue-Lucia™ TLR2 and HEK-Blue-Lucia™ TLR4 cells.
Fluorescent TLR3 labeling
Flow cytometry
Fluorescent microscopy
Confocal microscopy
TLR3 activation
Each lot is functionally tested and validated.
Spectral Properties of Rhodamine
- Excitation λ max: 546 nm
- Emission λ max: 576 nm
CONTENTS
Contents
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Product:Poly(I:C) (LMW) Rhodamine
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Cat code:tlrl-piwr
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Quantity:10 µg
1.5 ml sterile endotoxin-free water
Shipping & Storage
- Shipping method: Room temperature
- -20°C
- Avoid repeated freeze-thaw cycles
- Protect from light
Storage:
Caution:
DOCUMENTS
Documents
Technical Data Sheet
Safety Data Sheet
Certificate of analysis
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