Poly(I:C) (HMW) Fluorescein
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Cat.code:
tlrl-picf
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ABOUT
Fluorescein-labeled poly(I:C) (HMW)
Poly(I:C) Fluorescein was chemically labeled by covalent coupling of a fluorescein probe containing a reactive alkylating group. This confers fluorescent properties to poly(I:C) (HMW) whilst retaining TLR3 recognition properties.
Polyinosinic-polycytidylic acid (poly(I:C)) is a synthetic analog of double stranded RNA (dsRNA), a molecular pattern associated with viral infection.
Both natural and synthetic dsRNAs are known to induce type I interferons (IFN) and other cytokines production. Poly(I:C) is recognized by Toll-like receptor 3 (TLR3).
All products are for research use only, and not for human or veterinary use.
SPECIFICATIONS
Specifications
TLR3
10 ng/ml - 10 μg/ml
100 µg/ml in water
The absence of bacterial contamination (e.g. lipoproteins and endotoxins) is confirmed using HEK-Blue-Lucia™ TLR2 and HEK-Blue-Lucia™ TLR4 cells.
Fluorescent TLR3 labeling
Flow cytometry
Fluorescent microscopy
Confocal microscopy
TLR3 activation
Each lot is functionally tested and validated.
Spectral Properties of Fluorescein
- Excitation λ max: 492 nm
- Emission λ max: 518 nm
CONTENTS
Contents
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Product:Poly(I:C) (HMW) Fluorescein
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Cat code:tlrl-picf
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Quantity:10 µg
2 ml sterile endotoxin-free water
Shipping & Storage
- Shipping method: Room temperature
- -20°C
- Avoid repeated freeze-thaw cycles
- Protect from light
Storage:
Caution:
DOCUMENTS
Documents
Technical Data Sheet
Safety Data Sheet
Certificate of analysis
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