Poly(I:C) (HMW) Fluorescein - TLR3 Agonist

Fluorescent-labeled poly(I:C) (HMW)

ABOUT

Fluorescein-labeled poly(I:C) (HMW)

Poly(I:C) Fluorescein was chemically labeled by covalent coupling of a fluorescein probe containing a reactive alkylating group. This confers fluorescent properties to poly(I:C) (HMW) whilst retaining TLR3 recognition properties.

Polyinosinic-polycytidylic acid (poly(I:C)) is a synthetic analog of double stranded RNA (dsRNA), a molecular pattern associated with viral infection.

Both natural and synthetic dsRNAs are known to induce type I interferons (IFN) and other cytokines production. Poly(I:C) is recognized by Toll-like receptor 3 (TLR3).

All products are for research use only, and not for human or veterinary use.

SPECIFICATIONS

Specifications

Working concentration

10 ng/ml - 10 μg/ml

Appearance (color)
Pale yellow
Quality control

Each lot is functionally tested and validated.

CONTENTS

Contents

  • Product: 
    Poly(I:C) (HMW) Fluorescein
  • Cat code: 
    tlrl-picf
  • Quantity: 
    10 µg
Includes:

2 ml sterile endotoxin-free water

Notes:

Spectral Properties of Fluorescein

Excitation λ max: 492 nm
Emission λ max: 518 nm
 

Shipping & Storage

  • Shipping method:  Room temperature

    • Storage:

    • -20°C

    Caution:

    • Avoid repeated freeze-thaw cycles
    • Protect from light

DOCUMENTS

Documents

Poly(I:C) (HMW) Fluorescein

Technical Data Sheet

Safety Data Sheet

Certificate of analysis

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Citations

CUSTOMER SERVICE & TECHNICAL SUPPORT

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