pFUSEN-hG2Fc

Fc-fusion protein expression plasmid - Human IgG2

ABOUT

pFUSEN-hG2Fc is a cloning plasmid for the generation of a Fc-fusion protein expressing the Fc region (CH2 and CH3 domains) of the human IgG2 heavy chain and the hinge region.

Human IgG2-Fc displays low affinity towards FcγRs and complement receptors. This Fc domain is more suitable for applications for which ADCC and CDC are not desirable.

All products are for research use only, and not for human or veterinary use.

SPECIFICATIONS

Specifications

Applications

in vitro or in vivo transfection.

Species
Human
Gene
Human IgG2-Fc
Tag
Fc, C-ter
Plasmid backbone
pFUSEN
Antibiotic resistance
Zeocin®
Gene promoter
Human EF1α/HTLV hybrid promoter
Signal sequence
Human IL2 signal sequence
Purification
Ion-exchange chromatography
Reconstitution buffer
Endotoxin-free water (not provided)
Tested applications

in vitro transfection

Quality control

Plasmid construct is confirmed by restriction analysis and full-length open reading frame (ORF) sequencing.

CONTENTS

Contents

  • Product: 
    pFUSEN-hG2Fc
  • Cat code: 
    pfcn-hg2
  • Quantity: 
    20 µg
Includes:

1 ml of Zeocin® (100 mg/ml)

Shipping & Storage

  • Shipping method:  Room temperature

    • Storage:

    • -20°C
    Stability: Reconstituted product is stable for 1 year at -20 °C.

DOCUMENTS

Documents

pFUSEN-hG2Fc

Technical Data Sheet

Safety Data Sheet

Certificate of analysis

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Citations

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